Tuesday, November 24, 2009

Chantix vs. Zyban – Comparison between two leading prescription drugs

Chantix and Zyban are the two popular prescription medicines which help smokers break their smoking habit. Although, both these quit smoking medications work towards a common goal, they differ from each other in more ways than one.

Varenicline is a smoking cessation pill which has been particularly designed to reduce nicotine craving and withdrawal symptoms that are commonly found in smokers who are in the process of quitting smoking. Varenicline works by blocking the very receptors in the brain that are linked to nicotine addiction. While bupropion was primarily an antidepressant that was later approved for use as a smoking cessation medicine. In fact, the comparative study shows that varenicline, even in lower dosages, is far more effective than bupropion; it performs better in the short term as well as in the long term.

The Chantix vs. Zyban study reveals some interesting differences. Chantix vs. Zyban differences include:

• While Chantix is manufactured by Pfizer, GlaxoSmithKline manufactures Zyban
• Varenicline is a smoking cessation medicine while Bupropion is an aid to smoking cessation treatment
• Chantix was approved on May 11, 2006 while Zyban was approved on May 14, 1997, by the FDA
• While varenicline is designed to reduce nicotine cravings and withdrawal symptoms, bupropion was primarily designed to treat a condition called major depressive disorder
• Chantix blocks the nicotine receptors in the brain while Zyban’s ability to help patients abstain from smoking is unknown
• Varenicline tartrate is the active ingredient in Chantix while the active ingredient in Zyban is bupropion hydrochloride
• A 12 week smoking cessation study shows a success rate of 44% for varenicline and 29.5 % for bupropion
• 1 year study shows 22% abstinence with Chantix and 16% abstinence with Zyban
• While the varenicline dosage is 1mg twice daily, Bupropion is 150mg twice daily, which is comparatively much higher and yet less effective
• Varenicline must not be used in combination with other smoking cessation medicines while a combination treatment of bupropion and nicotine replacement therapy may be prescribed

Having mentioned all the major varenicline advantages over Bupropion, you should buy Chantix to quit smoking because it is the only approved drug that can facilitate the process of quitting without the nagging withdrawal symptoms. If you buy Chantix to quit smoking, it will convince your brain that you have the amount of nicotine you want – without actually having it. If you decide to buy Chantix, a nicotine-free treatment, to quit smoking, you can easily find it in all accredited pharmacies as well as online, throughout the US, but only with a valid doctor’s prescription.

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